Environmental fate and toxicology of clomazone.

نویسندگان

April R Van Scoy

Ronald S Tjeerdema

چکیده

Clomazone, an isoxazolane herbicide, was first registered for use in 1986 for pest grasses and broad leaf weeds. Although the exact mode of action is still unclear, it is well documented that clomazone causes bleaching of foliar structures; the clomazone metabolite 5-ketoclomazone is regarded to cause the bleaching and to be the ultimate plant toxicant. Although clomazone exhibits low mammalian toxicity and is selective towards certain plant species, studies have shown that it does inhibit AChE and catalase activities. In addition, it has been found to be highly toxic to aquatic invertebrates, in particular mysid shrimp.Clomazone has a low Henry's law constant and moderate vapor pressure, and thus may volatilize from dry soils. Photolysis represents a minor dissipationpathway; however, clomazone can be photolytically degraded under both direct and indirect conditions. Clomazone has high water solubility, and it is often assumed to undergo hydrolysis easily; unfortunately, this is not the case. Clomazone is stable over a wide pH range and does not hydrolyze. Clomazone has a weak to moderates oil adsorption coefficient; therefore, its affinity to sorb to soil is minimal, rendering it a potential threat to groundwater supplies.Microbial metabolism is the major degradation pathway, resulting in products such as 5-hydroxyclomazone, hydroxymethylclomazone, 2-chlorobenzyl alcohol and 3'-hydroxyclomazone. Although clomazone has not been shown to degrade viahydrolysis, it nonetheless represents a potential threat to aquatic organisms. With this in mind, caution should be taken when applying clomazone or when draining fields that have detectable clomazone residues.

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